What It Is
Doxofylline belongs to the xanthine group of medicines, the same broad family as theophylline. It is taken by mouth as tablets or syrup.
What It's Used For
Doxofylline is generally used to relieve symptoms of asthma and chronic obstructive pulmonary disease (COPD), including wheezing, cough, and breathlessness.
How It Works
Doxofylline relaxes the muscles around the airways, which opens them and improves airflow. Unlike theophylline, it has little effect on adenosine receptors, and this is thought to be why it may cause fewer side effects such as palpitations and nervousness, and fewer interactions with other medicines.
History and Regulatory Status
Doxofylline was developed in Italy and is marketed in a number of countries, including India, where it is widely prescribed. It is not approved for use in some countries, such as the United States. It is available as a generic prescription medicine, and its place in treatment is usually as an add-on or alternative to inhaled therapy.